Resources for Animal Users


Animal Care and Use Program information
 
USDA Class R Research Facility Registration
Number: 86-R-0003
Expiration Date: August 24, 2016
 
PHS Animal Welfare Assurance
Assurance Number: A3248-01
Expiration Date: August 31, 2019
 
AAALAC (accredited since 1969)
Accreditation Number: 000163
Status: Continued Full Accreditation
 
Some grant applications/submissions require a description of the Animal Care and Use Program. A sample description is available here.

General information for new PIs
 
Allergy Alert Sign: Print and place on the outside of the doors to areas where animals are used. This sign is used to alert non-animal users to the potential for allergens and to provide information on how to get a respirator, if desired.
 
Emergency Contact Sign: Print, complete and place on the inside of the doors to areas where animals are used. This sign is used in the event that there is an emergency and first responders find animals in the lab. It also provides contact information for animal welfare issues, as required by regulation.
 
Animal Hazards Checklist: Print, complete and file as appropriate. This is part of the Occupational Health Program associated with animal use. The form is a prompt to look for hazards and to deal with them in a timely manner. On the yearly anniversary of your protocol, the IACUC Office will send an Annual Status Report. One of the questions will be a prompt to review the Animal Hazards Checklist.
 
Surgery and Post-Operative Monitoring Form: This is a sample surgical record. Feel free to use this form or adapt it to what works for you. These are the records that the IACUC review during the semi-annual inspections. Note that surgical records must be accessible during IACUC inspections. We suggest using a binder to keep all records centrally and making copies for individual lab notebooks.
 
Drugs: We look at storage, grade and expiration date of clinical drugs, e.g., isoflurane, ketamine, xylazine, ophthalmic ointment and surgical glue. These types of drugs should be pharmaceutical grade and not expired. A description of pharmaceutical grade for the IACUC purposes is found here.
 
Ketamine and ketamine cocktails should be stored as for controlled substances (for more information contact RLSS). The IACUC do not inspect the DEA paperwork associated with controlled substances, but we are required that they are stored appropriately. Anesthetic cocktails must be stored and labelled as described here.
 
Surgical location This should be away from heavy traffic areas, if at all possible. There should also be a physically separate area for preparation of the animal (hair removal, surgical scrub). This can be on the same bench, but it must be a distinct area from the surgical location.
 
CO2 euthanasia: This guidance describes the type of chamber, CO2 source, flow meter and method for confirming death, that meet the regulations.
 

Animal health and safety
  • IACUC Office 626-5304, 626-1247
  • University Animal Care
  • University Animal Care on-call veterinarian - phone numbers are posted in each UAC animal facility

Human health and safety

Veterinary resources

Resources for wildlife researchers
 

Signs of mouse pain and distress
 
The following article describes the development of the "mouse grimace scale", which is a method for determining levels of pain by examining facial expressions. The article includes clear pictures and descriptions of the facial expressions:
 
Langford, Bailey, Chanda, et al., (2010). Coding of facial expressions of pain in the laboratory mouse. Nature Methods, 7:447-449.
 
The following article describes methods for determining the health status of mice, and provides guidance on establishing study endpoints based on health status:
 
Ullman-Culleré and Foltz (1999). Body condition scoring: a rapid and accurate method for assessing health status in mice. Laboratory Animal Science, 49:319-323.
 
The articles can be accessed through E-Journals at the UA library.

Use of invertebrate models in research
 
A review article describing the use of invertebrate animal models in research was recently published:
 
Wilson-Sanders S.E. (2011). Invertebrate Models for Biomedical Research, Testing, and Education. ILAR Journal, 52(2):126-152.
 
The article can be accessed through E-Journals at the UA library.

Other IACUC forms
 
     
     Report Misconduct
Ethics Hotline


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