Resources for Animal Users


Animal health and safety

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Animal Welfare Information Center (AWIC) training materials
 
PowerPoint from September 21, 2010 workshop: Meeting the Information Requirements of the Animal Welfare Act

Resources for wildlife researchers
 

Signs of mouse pain and distress
 
The following article describes the development of the "mouse grimace scale", which is a method for determining levels of pain by examining facial expressions. The article includes clear pictures and descriptions of the facial expressions:
 
Langford, Bailey, Chanda, et al., (2010). Coding of facial expressions of pain in the laboratory mouse. Nature Methods, 7:447-449.
 
The following article describes methods for determining the health status of mice, and provides guidance on establishing study endpoints based on health status:
 
Ullman-Culleré and Foltz (1999). Body condition scoring: a rapid and accurate method for assessing health status in mice. Laboratory Animal Science, 49:319-323.
 
The articles can be accessed through E-Journals at the UA library.

Use of invertebrate models in research
 
A review article describing the use of invertebrate animal models in research was recently published:
 
Wilson-Sanders S.E. (2011). Invertebrate Models for Biomedical Research, Testing, and Education. ILAR Journal, 52(2):126-152.
 
The article can be accessed through E-Journals at the UA library.
 

Description of animal research in scientific publications
 
Guidance for the Description of Animal Research in Scientific Publications outlines the information that should be included in scientific papers regarding animal studies to ensure that the study can be replicated.

Animal Care and Use Program accreditation information
 
The following documents are often required when applying for grants:
  • AAALAC Accreditation document
  • OLAW Animal Welfare Assurance Number
  • USDA Animal Welfare Act Registration
These documents can be accessed here.

Description of UAC Care and Use Policy for submission to granting agencies
 
Some grant applications/submissions require a description of the Animal Care Program. A sample description is provided.
 
The Animal Care and Use Program is centralized under the Office of the Vice President for Research (VPR). Oversight for the program is vested in the Department of University Animal Care (UAC) and with the Institutional Animal Care and Use Committee (IACUC). The Director of UAC reports to the VPR. UAC is responsible for overseeing all animal care and husbandry functions for the University. All conventional laboratory animal facilities are under the direct control of UAC. Facilities housing non-traditional species (reptiles, amphibians, wild birds) are staffed by the individual departments or investigators, but UAC provides veterinary and husbandry oversight and has the authority to make changes in management of these facilities. The University Farms are operated by the College of Agriculture, with oversight by the UAC Farm Animal Veterinarian.
 
The IACUC provides oversight for the total animal care and use program. The committee is appointed by the University President who is the Chief Executive Officer. The VPR is the Institutional Official, and the IACUC report to the VPR as mandated by PHS Policy and regulations of the Animal Welfare Act. The IACUC Committee maintains a membership of 15-20 members, including veterinarians, scientists, and community members and reviews all research studies and University courses which require the use of any animal species, except invertebrates, living or dead. The Committee makes semi-annual inspections of all facilities, laboratories and farms where animals are housed or used for 12 hours or more and performs semi-annual programmatic reviews. Committee members, or designees, inspect research laboratories to observe procedures to assure animals are used appropriately and are receiving humane treatment. Through the expertise of the UAC staff and other specialists, the Committee provides training for all who use or care for animals. Access to animal facilities is limited to those who have received IACUC certification.
 
The entire animal care and use program and its associated facilities and farms are AAALAC accredited. Three central facilities house conventional laboratory animals. The Arizona Health Sciences Central Facility (34,000 sq ft) serves investigators on the North Campus. The Central Animal Facility (25,000 sq ft) and adjacent Veterinary Science/Microbiology Facility (2,000 sq ft) serve users on the Main Campus. As facilities are operated centrally, animals can be moved between facilities, as needed, to meet the housing needs of investigators. Several satellite facilities house non-traditional species such as fish, reptiles and birds. The University also maintains domestic farm animals at the Campbell Avenue Farm and the West Campus Agricultural Center.
 
     
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